Developer Upsilon Alpha's Nucleogenesis is an educational spin on 2048 that teaches the basics of nuclear fusion. I won't pretend to be particularly knowledgeable on the topic, but the game's store page assures me that nucleogenesis "is the process of creating new elements through the process of fusion".
You have to imagine that you're gravity at the centre of a star. So instead of matching numbers, like in 2048, you'll spend your time fusing elements until the star's core erupts.
I published a game about the basics of nuclear fusion within stars... oh and it's free. from r/Physics
And it's all backed by an electronic cover of Camille Saint-Saëns' Danse macabre – an interesting and fun choice that adds some extra personality to the puzzling.
It's already grown quite popular over on r/Physics, where the game's trailer has received almost 3k upvotes. Also of note is the fact that the project was developed solely by a teenager in their spare time.
If you're looking to learn a little something about nuclear fusion, you'll find Nucleogenesis available for download now as a free-to-play title from over on Google Play.